High encapsulation efficiency of poloxamer-based injectable thermoresponsive hydrogels of etoposide

G Soni, KS Yadav - Pharmaceutical development and technology, 2014 - Taylor & Francis
… ETO-loaded injectable poloxamer-based thermoresponsive hydrogels could prolong the
release up to 48 h by E-Poloxamer407-PEG hydrogel and 24 h by E-P407-P188 hydrogel. The …

[HTML][HTML] Injectable poloxamer hydrogels for local cancer therapy

AC Marques, PC Costa, S Velho, MH Amaral - Gels, 2023 - mdpi.com
… (PT) injections allow high concentrations of therapeutic … promote retention of free or
encapsulated drugs at the tumor … thermoresponsive polymers, poloxamer-based hydrogels are …

[HTML][HTML] Injectable Thermoresponsive Hydrogels for Cancer Therapy: Challenges and Prospects

S Tanga, M Aucamp, P Ramburrun - Gels, 2023 - mdpi.com
… and into the systemic circulation via the high-pressure flow in the … chemotherapeutics into
poloxamer-based hydrogels is therefore … core, which helps to encapsulate hydrophobic drugs. …

Development of a Chemoablative, Thermoresponsive Hydrogel as a Drug Delivery Platform for Lung Cancer Applications

S Rossi - 2018 - repository.rcsi.com
… of the award of a higher degree of Doctor of Philosophy is my … Distribution of the injected
thermoresponsive hydrogel in an ex … the behaviour of the lead thermoresponsive hydrogels. …

Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial …

F ud Din, O Mustapha, DW Kim, R Rashid… - European Journal of …, 2015 - Elsevier
… considerable attention as an injectable depot system in tissue … because of its relatively high
entrapment efficiency (90%) and … In the poloxamer-based DRTH, the threshold in syringe-…

[HTML][HTML] In situ hydrogel formulation for intra-articular application of diclofenac sodium-loaded polymeric nanoparticles

B Küçüktürkmen, UC Öz, A Bozkir - Turkish journal of …, 2017 - ncbi.nlm.nih.gov
… 188 polymers in thermosensitive hydrogel formulations due to … Poloxamer-based hydrogels
are biocompatible and can be … The highest encapsulation efficiency was obtained with F6 …

Rheological and drug delivery characteristics of poloxamer-based diclofenac sodium formulations for chronic wound site analgesia

J Russo, J Fiegel, NK Brogden - Pharmaceutics, 2020 - mdpi.com
… Poloxamer 407, a thermosensitive polymer that is a liquid at low temperatures but gels at
higher … Additionally, poloxamer 407 has been studied for use in a vehicle for local injection of a …

Novel in situ forming hydrogel microneedles for transdermal drug delivery

A Sivaraman, AK Banga - Drug delivery and translational research, 2017 - Springer
… -ionic triblock amphiphilic thermosensitive copolymer, poloxamer… in injectable routes where
the liquid form was injected and … -gel transition property of poloxamer-based formulation was …

Enhancement in bioavailability of ketorolac tromethamine via intranasal in situ hydrogel based on poloxamer 407 and carrageenan

C Li, C Li, Z Liu, Q Li, X Yan, Y Liu, W Lu - International journal of …, 2014 - Elsevier
… Intravenous injection of ketorolac tromethamine solution in normal … , CPH is an interesting
thermosensitive in situ hydrogel with … Effect of carrageenan on poloxamer-based in situ gel for …

Quercetin Loaded Cationic Solid Lipid Nanoparticles in a Mucoadhesive In Situ Gel—A Novel Intravesical Therapy Tackling Bladder Cancer

S Shawky, S Makled, A Awaad, N Boraie - Pharmaceutics, 2022 - mdpi.com
… ], etoposide [26] and doxorubicin [27], due to the high solubility of … entrapment efficiency for
various lipophilic drugs and ensure … Different poloxamer based in situ gels were prepared and …